Directions: Apply 1 - 2 times daily to dry skin on the face/body. Best used after cleansing with Avene Xeracalm Cleansing Oil. The D.E.F.I (Device for Exclusive Formula Integrity) means that no air can enter into the tube, meaning the product remains sterile and protected throughout use. Therefore STERILE COSMETICS products contain only essential ingredients for your skin. Available in a 200ml PumpTube or a 400ml Pump Bottle